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Ethier, Stephen
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phone 843-876-2537
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Academic Article A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.
Academic Article ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.
Academic Article Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells.
Academic Article The PHSRN sequence induces extracellular matrix invasion and accelerates wound healing in obese diabetic mice.
Academic Article Human breast cancer cell lines as models of growth regulation and disease progression.
Academic Article A bcl-xS adenovirus selectively induces apoptosis in transformed cells compared to normal mammary cells.
Academic Article Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data.
Academic Article Characterization of fibroblast growth factor receptor 2 overexpression in the human breast cancer cell line SUM-52PE.
Academic Article Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells.
Academic Article PTEN/MMAC1 overexpression decreases insulin-like growth factor-I-mediated protection from apoptosis in neuroblastoma cells.
Academic Article erbB-2 overexpression in human mammary epithelial cells confers growth factor independence.
Academic Article Signal transduction pathways: the molecular basis for targeted therapies.
Academic Article Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis.
Academic Article p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion.
Academic Article Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells.
Academic Article Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells.
Academic Article Genomic organization of the 8p11-p12 amplicon in three breast cancer cell lines.
Academic Article Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells.
Academic Article Integrin fibronectin receptors in matrix metalloproteinase-1-dependent invasion by breast cancer and mammary epithelial cells.
Academic Article SUM-159PT cells: a novel estrogen independent human breast cancer model system.
Academic Article Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells.
Academic Article BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants.
Academic Article Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells.
Academic Article Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells.
Academic Article Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer.
Academic Article Lack of RB protein correlates with increased sensitivity to UV-radiation-induced apoptosis in human breast cancer cells.
Academic Article Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells.
Academic Article Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor.
Academic Article Differential screening and mass mapping of proteins from premalignant and cancer cell lines using nonporous reversed-phase HPLC coupled with mass spectrometric analysis.
Academic Article LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Academic Article p38MAPK-activated AKT in HER-2 overexpressing human breast cancer cells acts as an EGF-independent survival signal.
Academic Article Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells.
Academic Article Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
Academic Article The potential of 2-deoxy-2[18F]fluoro-D-glucose (FDG) for the detection of tumor involvement in lymph nodes.
Academic Article Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.
Academic Article Amphiregulin as a novel target for breast cancer therapy.
Academic Article Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells.
Academic Article Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study.
Academic Article Epidermal growth factor receptor signaling and response of cancer cells to ionizing radiation.
Academic Article The influence of growth factors on the proliferative potential of normal and primary breast cancer-derived human breast epithelial cells.
Academic Article Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells.
Academic Article Editorial: Cost-effective analyses in Breast Cancer Research and Treatment [corrected].
Academic Article Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer.
Academic Article Influence of hormone and growth factor interactions on the proliferative potential of normal rat mammary epithelial cells in vitro.
Academic Article EGFR/Met association regulates EGFR TKI resistance in breast cancer.
Academic Article HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation.
Academic Article Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells.
Academic Article Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.
Academic Article ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.
Academic Article Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.
Academic Article The role of phosphatidylinositol 3'-kinase and its downstream signals in erbB-2-mediated transformation.
Academic Article Identifying and validating causal genetic alterations in human breast cancer.
Academic Article Enhanced in vitro proliferation and in vivo tumorigenic potential of mammary epithelium from BALB/c mice exposed in vivo to gamma-radiation and/or 7,12-dimethylbenz[a]anthracene.
Academic Article Survival of mammary epithelial cells from virgin female BALB/c mice following in vivo gamma irradiation.
Academic Article Detection of ductal dysplasia in mammary outgrowths derived from carcinogen-treated virgin female BALB/c mice.
Academic Article Carotenoids induce morphological changes in human mammary epithelial cell cultures.
Academic Article Insulin like growth factor-I independence in rat mammary carcinoma cells: a dominant phenotype in somatic cell hybrid experiments.
Academic Article erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line.
Academic Article Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines.
Academic Article Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo.
Academic Article The role of Ha-ras oncogenes in growth factor independence in rat mammary carcinoma cells.
Academic Article Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Academic Article Cleavage of beta-catenin by calpain in prostate and mammary tumor cells.
Academic Article Cooperative interactions of HER-2 and HPV-16 oncoproteins in the malignant transformation of human mammary epithelial cells.
Academic Article Comprehensive profiling of 8p11-12 amplification in breast cancer.
Academic Article Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.
Academic Article New guidelines for reporting of tumor marker studies in breast cancer research and treatment: REMARK.
Academic Article Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon.
Academic Article A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
Academic Article Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways.
Academic Article KUTE-BASE: storing, downloading and exporting MIAME-compliant microarray experiments in minutes rather than hours.
Academic Article Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells.
Academic Article Secretion of a TGF-beta-like growth inhibitor by normal rat mammary epithelial cells in vitro.
Academic Article Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.
Academic Article ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer.
Academic Article Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers.
Academic Article Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines.
Academic Article Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo.
Academic Article Transforming properties of 8p11-12 amplified genes in human breast cancer.
Academic Article Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.
Academic Article Knock-down of amphiregulin inhibits cellular invasion in inflammatory breast cancer.
Academic Article Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer.
Academic Article Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.
Academic Article cAMP levels in proliferating rat mammary epithelial cells in vitro and in vivo.
Academic Article Identification and functional analysis of 9p24 amplified genes in human breast cancer.
Academic Article Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.
Academic Article Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells.
Academic Article Serum-free culture conditions for the growth of normal rat mammary epithelial cells in primary culture.
Academic Article Morphological and histological characteristics of mammary dysplasias occurring in cell dissociation-derived murine mammary outgrowths.
Academic Article Factors influencing expression of mammary ductal dysplasia in cell dissociation-derived murine mammary outgrowths.
Academic Article Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node.
Academic Article Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2.
Academic Article Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification.
Academic Article BRCA1 protein level is not affected by peptide growth factors in MCF10A cell line.
Concept Disulfiram
Concept Alprostadil
Concept Insulin
Concept Extracellular Matrix
Concept Karyotyping
Concept Disease Models, Animal
Concept DNA Methylation
Concept Y-Box-Binding Protein 1
Concept Genes, erbB-2
Concept Breast
Concept Transforming Growth Factor beta
Concept Ionomycin
Concept Hybrid Cells
Concept NF-kappa B
Concept Heat-Shock Proteins
Concept Interferon-gamma
Concept Caspase 9
Concept Genes, cdc
Concept Androstadienes
Concept Ultraviolet Rays
Concept Neuregulins
Concept Flow Cytometry
Concept Human papillomavirus 16
Concept Tumor Suppressor Protein p53
Concept Prostatic Neoplasms
Concept Vaccines, DNA
Concept Genes, BRCA1
Concept Genes, Tumor Suppressor
Concept Recurrence
Concept PTEN Phosphohydrolase
Concept Oncogenes
Concept Vesicle-Associated Membrane Protein 2
Concept Cell Nucleus
Concept S Phase
Concept Cell Division
Concept Actins
Concept Gene Expression
Concept Matrix Metalloproteinase 1
Concept Cyclin-Dependent Kinases
Concept Forkhead Transcription Factors
Concept RNA Interference
Concept Retinoblastoma Protein
Concept DNA, Complementary
Concept Fluorescent Antibody Technique
Concept Telomere
Concept Chromosomal Instability
Concept Disease Progression
Concept CD8-Positive T-Lymphocytes
Concept HSP27 Heat-Shock Proteins
Concept Information Storage and Retrieval
Concept Carcinoma, Basal Cell
Concept Cell Adhesion Molecules
Concept Cell Adhesion
Concept rho GTP-Binding Proteins
Concept Internet
Concept Genes, Dominant
Concept Rats, Inbred Lew
Concept Genomics
Concept BALB 3T3 Cells
Concept Cyclin E
Concept NIH 3T3 Cells
Concept Dogs
Concept Chromones
Concept Progesterone
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Basement Membrane
Concept Mitogen-Activated Protein Kinase 1
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Trans-Activators
Concept Protein Biosynthesis
Concept Amino Acid Sequence
Concept Insulin-Like Growth Factor I
Concept TCF Transcription Factors
Concept Anticarcinogenic Agents
Concept Transforming Growth Factors
Concept Antineoplastic Agents
Concept Culture Media
Concept Calcium
Concept Precipitin Tests
Concept Carcinoma, Lobular
Concept Colorectal Neoplasms
Concept STAT3 Transcription Factor
Concept DNA Copy Number Variations
Concept Blotting, Western
Concept Cancer Vaccines
Concept Iodine Radioisotopes
Concept 3T3 Cells
Concept Tumor Stem Cell Assay
Concept Chemokine CXCL2
Concept Diabetes Mellitus
Concept Hydrocortisone
Concept Endoribonucleases
Concept Research Support as Topic
Concept Antibodies, Neoplasm
Concept Tumor Cells, Cultured
Concept Shc Signaling Adaptor Proteins
Concept Chromatin
Concept Clinical Trials as Topic
Concept Culture Media, Serum-Free
Concept Cell Line, Transformed
Concept Tritium
Concept DNA Primers
Concept Mitogen-Activated Protein Kinase 3
Concept Adenocarcinoma
Concept Transcription, Genetic
Concept beta Carotene
Concept Repressor Proteins
Concept Mammary Glands, Human
Concept Immune Sera
Concept Floxuridine
Concept Estrogens
Concept Exons
Concept Genes, ras
Concept Codon
Concept Chromosomes, Human, Pair 9
Concept Toll-Like Receptor 2
Concept Transferrin
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept HT29 Cells
Concept Cells, Cultured
Concept Genes, Neoplasm
Concept Cell Separation
Concept CCN Intercellular Signaling Proteins
Concept T-Lymphocytes
Concept Phosphoric Monoester Hydrolases
Concept Cytoplasm
Concept Transforming Growth Factor beta1
Concept Genes, p53
Concept Antineoplastic Agents, Hormonal
Concept Monocytes
Concept Somatomedins
Concept Xenograft Model Antitumor Assays
Concept Cell Proliferation
Concept Caspase 8
Concept Survival Rate
Concept User-Computer Interface
Concept Cattle
Concept Chaperonin Containing TCP-1
Concept Intracellular Fluid
Concept Homeodomain Proteins
Concept beta Catenin
Concept CpG Islands
Concept Drug Screening Assays, Antitumor
Concept Hepatocyte Growth Factor
Concept Keratins
Concept Comparative Genomic Hybridization
Concept Connective Tissue Growth Factor
Concept Molecular Probes
Concept Adaptor Proteins, Signal Transducing
Concept Fibroblast Growth Factor 7
Concept Interleukin-1
Concept Estradiol
Concept Epithelium
Concept Proto-Oncogene Proteins c-myc
Concept Calpain
Concept Genes, Reporter
Concept Carcinoma, Non-Small-Cell Lung
Concept Caspases
Concept Ethanolamines
Concept Transcription Factor AP-1
Concept GTP Phosphohydrolases
Concept Histological Techniques
Concept Antibodies, Monoclonal
Concept DNA Damage
Concept Cell Membrane
Concept Cluster Analysis
Concept ras Proteins
Concept Amino Acid Transport System y+
Concept Transforming Growth Factor alpha
Concept Cell Culture Techniques
Concept Vanadates
Concept Proto-Oncogene Proteins pp60(c-src)
Concept Fatty Acids
Concept Cost-Benefit Analysis
Concept Carcinoma
Concept Bucladesine
Concept Cytoskeleton
Concept Fibroblast Growth Factors
Concept Carotenoids
Concept Protein Tyrosine Phosphatases
Concept Benzoflavones
Concept Th1 Cells
Concept 9,10-Dimethyl-1,2-benzanthracene
Concept Interleukin-8
Concept Papillomaviridae
Concept Spheroids, Cellular
Concept Carcinoma, Squamous Cell
Concept Adenoviridae
Concept Bromodeoxyuridine
Concept Case-Control Studies
Concept Epidermal Growth Factor
Concept CCAAT-Enhancer-Binding Proteins
Concept Genes, myc
Concept Mucin-1
Concept Ethanolamine
Concept Extracellular Signal-Regulated MAP Kinases
Concept Proliferating Cell Nuclear Antigen
Concept Chromosomes, Human, Pair 8
Concept Gamma Rays
Concept Fluorodeoxyglucose F18
Concept CD4-Positive T-Lymphocytes
Concept Antimetabolites, Antineoplastic
Concept Fibroblast Growth Factor 1
Concept Dose-Response Relationship, Radiation
Concept Collagen
Concept Autoradiography
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 1
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept Staining and Labeling
Concept Codon, Nonsense
Concept Proto-Oncogene Proteins c-ret
Concept Genome-Wide Association Study
Concept Cell Growth Processes
Concept Peptide Hydrolases
Concept Cell Line
Concept Chromosome Deletion
Concept Integrin alpha4beta1
Concept Diterpenes
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Paclitaxel
Concept DNA Repair
Concept Chemokine CXCL1
Concept Culture Media, Conditioned
Concept Vaccination
Concept In Situ Hybridization, Fluorescence
Concept Deoxyglucose
Concept Neuregulin-1
Concept Chemokines
Concept Promoter Regions, Genetic
Concept Cesium Radioisotopes
Concept Epoxy Compounds
Concept Copper
Concept Azacitidine
Concept Carcinoma, Ductal, Breast
Concept Gene Silencing
Concept Cyclic AMP
Concept Base Sequence
Concept Alleles
Concept Fibroblast Growth Factor 2
Concept HCT116 Cells
Concept Immunohistochemistry
Concept Colonic Neoplasms
Concept Frameshift Mutation
Concept Cell Line, Tumor
Concept Molecular Sequence Data
Concept NFI Transcription Factors
Academic Article Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Academic Article KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
Academic Article SNAI2 modulates colorectal cancer 5-fluorouracil sensitivity through miR145 repression.
Academic Article Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer.
Academic Article Perspectives on Epidermal Growth Factor Receptor Regulation in Triple-Negative Breast Cancer: Ligand-Mediated Mechanisms of Receptor Regulation and Potential for Clinical Targeting.
Academic Article Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death.
Academic Article Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes.
Academic Article Reproducibility: changing the policies and culture of cell line authentication.
Academic Article Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer.
Academic Article The culture of cell culture practices and authentication--Results from a 2015 Survey.
Academic Article Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.
Academic Article Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERa in SUM-44 breast cancer cells and is associated with ERa over-expression in breast cancer.
Academic Article MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer.
Academic Article Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers.
Academic Article Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3.
Academic Article MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer.
Academic Article Oridonin inhibits aberrant AKT activation in breast cancer.
Academic Article ICOSL-augmented adenoviral-based vaccination induces a bipolar Th17/Th1 T cell response against unglycosylated MUC1 antigen.
Academic Article Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
Academic Article Eukaryotic initiation factor 4E-binding protein as an oncogene in breast cancer.
Academic Article Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer.
Academic Article Development and implementation of the SUM breast cancer cell line functional genomics knowledge base.
Concept Transcription Factor 7-Like 2 Protein
Concept Th17 Cells
Concept Class I Phosphatidylinositol 3-Kinases
Concept Antibodies, Monoclonal, Humanized
Concept MCF-7 Cells
Concept Polycomb Repressive Complex 2
Concept EGF Family of Proteins
Concept Amphiregulin
Concept Trastuzumab
Concept Enhancer of Zeste Homolog 2 Protein
Concept Src Homology 2 Domain-Containing, Transforming Protein 1
Concept Regulatory Factor X Transcription Factors
Concept X-Box Binding Protein 1
Concept Cancer-Associated Fibroblasts
Concept rhoC GTP-Binding Protein
Concept Chemokine CXCL16
Concept HEK293 Cells
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